Beam Therapeutics Inc. (BEAM) H.C. Wainwright 27th Annual Global Investment Transcript


Beam Therapeutics Inc. (NASDAQ:BEAM) H.C. Wainwright 27th Annual Global Investment Conference September 8, 2025 10:30 AM EDT

Company Participants

John Evans – CEO & Director

Conference Call Participants

Patrick Trucchio – H.C. Wainwright & Co, LLC, Research Division
Unknown Attendee

Presentation

Patrick Trucchio
MD of Equity Research & Senior Healthcare Analyst

Great. Good morning, everyone, and thank you for joining H. C. Wainwright’s 27th Annual Global Investment Conference, September 8 to September 10, 2025. My name is Patrick Trucchio. I’m the senior healthcare at H. C. Wainwright. It’s my pleasure to introduce our next company, and next speaker. It’s my pleasure to welcome Beam Therapeutics, a biotechnology company, leveraging its fully integrated precision genetic medicine platform to bring lifelong cures to patients suffering from serious diseases.

Beam’s suite of gene editing technology is anchored by base editing, a proprietary technology, that is designed to enable precise predictable and efficient single-based changes at targeted genomic sequences without making double-stranded breaks in the DNA. And with that, it’s my pleasure to introduce the CEO, John Evans. Welcome to the fireside chat today.

John Evans
CEO & Director

Great to be here. Thank you.

Question-and-Answer Session

Patrick Trucchio
H.C. Wainwright & Co, LLC, Research Division

So first, maybe you can briefly introduce Beam’s base editing platform, how it differs from first-generation gene editing and what it enables clinically?

John Evans
CEO & Director

Great. So Beam is working on a next-generation version of CRISPR gene editing. It’s called base editing. And with gene editing in general and CRISPR specifically, we have the amazing ability to target the genome very precisely. We can choose one spot across 3 billion different letters of your genes, where there’s an error and go in and try to fix it. What is different about what we do is that once we get to that target site, we



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